C-H Bond Functionalizations with Palladium(II): Intramolecular Oxidative Annulations of Arenes.
نویسندگان
چکیده
Oxidative annulations for the synthesis of carbocycles were developed using a catalytic palladium(II) system. Indoles with pendant olefin tethers were oxidatively cyclized to form annulated products. Electron-rich aromatic systems were also investigated, culminating in the synthesis of benzofurans and dihydrobenzofurans by a similar protocol. These reactions were demonstrated to proceed by an initial C-H bond functionalization event, followed by olefin insertion and β-hydride elimination.
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ورودعنوان ژورنال:
- Tetrahedron
دوره 64 28 شماره
صفحات -
تاریخ انتشار 2008